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        In a cleanroom the concentration of airborne particles is controlled by means of air filtration and airflow management. The cleanroom is constructed and operated in a manner designed to minimize the introduction, generation, and retention of particles inside the room. A cleanroom has a controlled level of contamination that is specified by the number of particles per cubic meter at a specified particle size. an aseptic cleanroom is operated with strict controls designed to minimize the presence of microorganisms.